Effectiveness of the shorter MDR regimen in the management of tuberculosis: Shortfall in the outcome of disease a multidimensional approach and evaluation for a better alternative
| Autor: | Prasanta Kumar Das, Somtirtha B Ganguly |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Biomedical and Biotechnology Research Journal, Vol 4, Iss 2, Pp 143-147 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2588-9834 2588-9842 |
| DOI: | 10.4103/bbrj.bbrj_131_19 |
| Popis: | Background: Shorter multidrug-resistant (MDR) regimen has proved to be very effective in some of the developing nations such as Bangladesh and several African countries. Various shortcomings in the execution of long-term MDR regimen have prompted for adapting the shorter regimen in India. The study explored the experience of the programmatic management of tuberculosis by a shorter regimen in West Bengal, India. Materials and Methods: Retrospective analysis of the data included the outcome analysis of the cured, lost to followup, treatment completed, treatment failure, treatment regimen changed and died. These attributes were analyzed. Results: Of the total 203 cases, cure rate accounted for 44.3%. Lost to follow-up was found to be 13.7%, in which alternative dispute resolution accounted for the major cause. A substantial amount of INH resistance is seen among the follow-up culture positive cases speculating the role of ethionamide in the regimen. |
| Databáze: | Directory of Open Access Journals |
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