Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm

Autor: J. J. Corrales, C. Robles-Lázaro, A. I. Sánchez-Marcos, M. C. González-Sánchez, P. Antúnez-Plaza, J. M. Miralles
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Case Reports in Endocrinology, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-6501
2090-651X
DOI: 10.1155/2016/6785925
Popis: Adrenocortical oncocytic neoplasms (oncocytomas) are extremely rare; only approximately 159 cases have been described so far. The majority are nonfunctional and benign. We describe an unusual case of a functional oncocytoma secreting an excess of glucocorticoids (cortisol) and androgens (androstenedione and DHEAS), a pattern of plurihormonal cosecretion previously not reported in men, presenting with endocrine manifestations of Cushing’s syndrome. The neoplasm was considered to be of uncertain malignant potential (borderline) according to the Lin-Weiss-Bisceglia criteria.
Databáze: Directory of Open Access Journals