Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study
| Autor: | Nicole Rosa de Freitas, Luísa Belluco Guerrini, Luis Augusto Esper, Michyele Cristhiane Sbrana, Gisele da Silva Dalben, Simone Soares, Ana Lúcia Pompéia Fraga de Almeida |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Applied Oral Science, Vol 26, Iss 0 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1678-7765 1678-7757 |
| DOI: | 10.1590/1678-7757-2017-0244 |
| Popis: | Abstract The repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M. The animals were killed 30 days postoperatively. After tissue processing, bone regeneration was evaluated by histomorphometric analysis and statistical analyses were performed (Tukey test, p |
| Databáze: | Directory of Open Access Journals |
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