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Lakshmi Pallavi Ganipineni,1 Bernard Ucakar,1 Nicolas Joudiou,2 John Bianco,1 Pierre Danhier,2 Mengnan Zhao,1 Chiara Bastiancich,1 Bernard Gallez,2 Fabienne Danhier,1,* Véronique Préat1,* 1Université catholique de Louvain, Advanced Drug Delivery and Biomaterials Research Group, Louvain Drug Research Institute, Brussels, Belgium; 2Université catholique de Louvain, Louvain Drug Research Institute, NEST Nuclear and Electron Spin Technologies Platform, Brussels, Belgium *These authors contributed equally to this work Introduction: Glioblastoma (GBM) therapy is highly challenging, as the tumors are very aggressive due to infiltration into the surrounding normal brain tissue. Even a combination of the available therapeutic regimens may not debulk the tumor completely. GBM tumors are also known for recurrence, resulting in survival rates averaging |