Quantitative outcomes of a type 2 single arm hybrid effectiveness implementation pilot study for hypertension-HIV integration in Botswana

Autor: Thato Moshomo, Tendani Gaolathe, Mareko Ramotsababa, Onkabetse Julia Molefe-Baikai, Edwin Mogaetsho, Evelyn Dintwa, Pooja Gala, Ponego Ponatshego, Laura M. Bogart, Nabila Youssouf, Khumo Seipone, Amelia E. Van Pelt, Kara Bennett, Shabbar Jaffar, Maliha Ilias, Veronica Tonwe, Kathleen Wirth Hurwitz, Kago Kebotsamang, Karen Steger-May, Lisa R. Hirschhorn, Mosepele Mosepele
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Implementation Science Communications, Vol 5, Iss 1, Pp 1-13 (2024)
Druh dokumentu: article
ISSN: 2662-2211
DOI: 10.1186/s43058-024-00620-w
Popis: Abstract Background Successful HIV treatment programs have turned HIV into a chronic condition, but noncommunicable diseases such as hypertension jeopardize this progress. Hypertension control rates among people with HIV (PWH) are low owing to gaps in patient awareness, diagnosis, effective treatment, and management of both conditions at separate clinic visits. Integrated management, such as in our study, InterCARE, can enhance HIV-hypertension integration and blood pressure (BP) control. Methods Our pilot study was conducted in two Botswana HIV clinics between October 2021 and November 2022. Based on our formative work, we adopted three main strategies; Health worker training on HTN/cardiovascular disease (CVD) management, adaptation of HIV Electronic Health Record (EHR) for HTN/CVD care, and use of treatment partners to support PWH with hypertension for implementation. We employed the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework to assess implementation effectiveness and outcomes for BP control at baseline, 6 and 12 months. HIV viral load (VL) suppression was also measured to assess impact of integration on HIV care. Results We enrolled 290 participants; 35 (12.1%) were lost to follow-up, leaving 255 (87.9%) at 12-months. Median age was 54 years (IQR 46–62), and 77.2% were females. Our interventions significantly improved BP control to
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