| Autor: |
Owen P. Leary, Matthew Hagan, Patricia L. Zadnik Sullivan, Abigail McElroy, Sohail Syed, David D. Liu, John E. Donahue, Keith-Austin Scarfo, Alexios G. Carayannopoulos, Justin Li, Konstantina Svokos, Jared S. Fridley, Ziya L. Gokaslan, Adetokunbo A. Oyelese, Petra M. Klinge |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Interdisciplinary Neurosurgery, Vol 33, Iss , Pp 101773- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2214-7519 |
| DOI: |
10.1016/j.inat.2023.101773 |
| Popis: |
Introduction: Diagnosis, pathophysiology, and rationale for surgical intervention in adult-onset tethered cord syndrome (ATCS) remain controversial. In this population, comorbid degenerative spinal disease (DSD) and prior trauma may sometimes distract from radiologic evidence of TCS. Methods: We retrospectively reviewed electronic medical records of consecutive patients (2011–2019) presenting with back pain, lower extremity neurological symptoms, and/or urinary or bowel symptoms, who had radiologic evidence of fatty filum terminale (FT) and/or low-lying conus (LLC) in the setting of degenerative spine disease, and who underwent surgical detethering of the spinal cord. Medical history, presenting symptoms, MRI reports, and postoperative outcome data were collected and summarized. FT specimens were analyzed using histology and transmission electron microscopy (TEM). Correlation of preoperative characteristics with outcome were assessed using multivariate logistic regression. Results: Forty-nine patients (mean age 47.9 ± 17.6 years) diagnosed with ATCS were included. Nineteen (38.8 %) had undergone prior spine surgery. From baseline to one-month post-op, the proportion of patients with neurologic symptoms decreased from 100 % to 77.8 % (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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