Hepato-splenic T-cell lymphoma and Crohn’s disease

Autor: Mouna GOURINE, Samir SAADI, Rafik ELAOUFI, Mohammed ARRAR, Anwer CHERRAK, Mohammed Amine CHAM
Jazyk: English<br />French
Rok vydání: 2022
Předmět:
Zdroj: Journal de la Faculté de Médecine d'Oran, Vol 1, Iss 3 (2022)
Druh dokumentu: article
ISSN: 2571-9874
2602-6511
Popis: Introduction - Hepato-splenic T-cell lymphoma is an extra-nodal lymphoma that belongs to the group of non Hodgkin lymphomas. The clinical presentation is usually systemic with constitutional symptoms, splenomegaly and/or hepatomegaly, in the absence of lymphadenopathy. The intra-sinusoidal infiltration of the bone marrow, the liver and/or the spleen by atypical T lymphocytes at immunophenotyping provides the diagnosis of hepato-splenic T-cell lymphoma. It arises in young people, more often in males, with a bad prognosis. It may occur in people without any previous known diseases, but also in immunocompromised patients, with hemopathies or dysimmunitary diseases as inflammatory bowel diseases. Observation - We report here the observation of a woman with hepatosplenic T-cell lymphoma and misdiagnosed Crohn’s disease.
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