Green tea catechins adsorbed on the murine pharyngeal mucosa reduce influenza A virus infection

Autor: Shintaro Onishi, Takuya Mori, Hidetoshi Kanbara, Taichi Habe, Noriyasu Ota, Yuki Kurebayashi, Takashi Suzuki
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Functional Foods, Vol 68, Iss , Pp 103894- (2020)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2020.103894
Popis: Green tea consumption reduces influenza incidence in human populations. However, where and how green tea exerts its anti-viral activities remain unclear. Here, we examined the adsorption of green tea catechins on the pharyngeal mucosa at 3–60 min after ingestion of green tea extract (GTE) and the role this adsorption plays in preventing influenza A virus (IAV) infection in BALB/c mice. Green tea catechins were adsorbed on the pharyngeal mucosa for up to 60 min after GTE ingestion. The anti-IAV activity of GTE was dose dependent (p
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