| Autor: |
B.O. Estupiñán-Díaz, L.M. Morales-Chacón, I. García-Maeso, L. Lorigados-Pedre, M. Báez-Martín, M.E. García-Navarro, O. Trápaga-Quincoses, N. Quintanal-Cordero, J. Prince-López, J.E. Bender-del Busto |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Neurología (English Edition), Vol 30, Iss 2, Pp 90-96 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2173-5808 |
| DOI: |
10.1016/j.nrleng.2013.06.014 |
| Popis: |
Introduction: Corpora amylacea (CoA) are present in about 60% of atrophic hippocampi resected from patients with drug resistant temporal lobe epilepsy (DRTLE). They have also been described in the lateral temporal neocortex, although less frequently. Objective: The objective is to measure the presence, distribution and density of CoA in the lateral temporal lobes of patients with DRTLE and focal cortical dysplasia (FCD), also examining how CoA density may be linked to demographic and clinical traits. Methods: Resected tissue from 35 patients was analysed. CoA density was assessed with a semi-quantitative scale according to the criteria established by Cherian et al. Results: Presence of CoA in the neocortex of nine patients was associated with hippocampal sclerosis (FCD type IIIa, seven cases), dysembryoplastic neuroepithelial tumour (FCD type IIIb, one case), and cavernous angioma (FCD type IIIC, 1 case). The meningeal surface (MS) was involved in all cases, and eight cases displayed CoA in the cerebral parenchyma (white matter) and around blood vessels. CoA density on the MS showed a negative correlation with age at seizure onset (r = −0.828, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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