Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

Autor: Muhammad Salem, Ahmed El‐Bardissy
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical Case Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.5136
Popis: Abstract Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too‐early dose intensification may have produced lamotrigine‐induced blood dyscrasia.
Databáze: Directory of Open Access Journals
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