HIV infection and the kidneys, Part II: Morphologic changes and their diagnostic significance

Autor: Basta-Jovanović Gordana M., Radojević Sanja M., Savin Marina, Terzić Tatjana, Nenadović Maja, Stojimirović Biljana, Škodrić Stevo, Nešić Vidosava, Dikman Steve
Jazyk: English<br />Serbian
Rok vydání: 2005
Předmět:
Zdroj: Srpski Arhiv za Celokupno Lekarstvo, Vol 133, Iss 5-6, Pp 258-261 (2005)
Druh dokumentu: article
ISSN: 0370-8179
DOI: 10.2298/SARH0506258B
Popis: HIV-infected patients may be faced with a variety of renal problem patterns. HIV-associated nephropathy is a unique pattern of sclerosing glomerulopathy and represents the most rapidly progressive form of focal segmental glomerulosclerosis. This study involved the examination of 32 renal biopsies: by light, immunofluorescence, and electron microscopy, in order to determine the most accurate and reliable diagnostic procedure. The findings show that the most sensitive and accurate procedure is electron microscopy, capable of detecting specific EM changes very early on, which is sufficient for the diagnosis of HIV-associated nephropathy.
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