Maternal bisphenol urine concentrations, fetal growth and adverse birth outcomes: A population-based prospective cohort

Autor: Chalana M. Sol, Charissa van Zwol - Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande, Susana Santos
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Environmental Health, Vol 20, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1476-069X
DOI: 10.1186/s12940-021-00747-6
Popis: Abstract Background Exposure to bisphenols may affect fetal growth and development. The trimester-specific effects of bisphenols on repeated measures of fetal growth remain unknown. Our objective was to assess the associations of maternal bisphenol urine concentrations with fetal growth measures and birth outcomes and identify potential critical exposure periods. Methods In a population-based prospective cohort study among 1379 pregnant women, we measured maternal bisphenol A, S and F urine concentrations in the first, second and third trimester. Fetal head circumference, length and weight were measured in the second and third trimester by ultrasound and at birth. Results An interquartile range increase in maternal pregnancy-averaged bisphenol S concentrations was associated with larger fetal head circumference (difference 0.18 (95% confidence interval (CI) 0.01 to 0.34) standard deviation scores (SDS), p-value
Databáze: Directory of Open Access Journals
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