Cytokines in the modulation of eosinophilia

Autor:	Faccioli Lúcia H, Vargaftig BB, Medeiros Alexandra I, Malheiros Adriana
Jazyk:	angličtina
Rok vydání:	1997
Předmět:	eosinophils helminth Parasites inflammation cytokines Microbiology QR1-502 Infectious and parasitic diseases RC109-216
Zdroj:	Memorias do Instituto Oswaldo Cruz, Vol 92, Iss suppl.2, Pp 109-114 (1997)
Druh dokumentu:	article
ISSN:	0074-0276 1678-8060
Popis:	In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis. We also describe the sequential release of TNF-alpha and IL-8 during the course of infection, and the interaction between these cytokines and IL-5 during infection. Finally we propose a new biological role for IL-5, at least in our model, as a modulator of IL-8 release and secretion.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/174e0c25010b4ad296a3eee1e7b18bc0 Zobrazit plný text záznamu View record in DOAJ