Effect of interferon on the development of Trypanosoma cruzi in tissue culture 'Vero' cells

Autor: R. R. Golgher, M. S. M. Bertelli, M. L. Petrillo-Peixoto, Z. Brener
Jazyk: angličtina
Rok vydání: 1980
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 75, Iss 1-2, Pp 157-160 (1980)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02761980000100015
Popis: Results are presented on the effects of interferon on the intracellular stages of T. cruzi in tissue culture "Vero" cells. Interferon was obtained by infecting monolayers of human amniotic cells with inactivated Newcastle disease virus. Interferon has not affected the cell infection by T. cruzi culture infective stages and neither has it prevented the transformation of amastigote into trypomastigote stages.Interferon obtido através da infecção de células amnióticas humanas por vírus inativado da doença de Newcastle foi incapaz de influir sobre a infectividade de formas de cultura do T. cruzi para células "Vero" de cultura de tecido. A transformação amastigota-tripomastigota também não foi afetada pelo interferon.
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