CA 19-9 as a serum marker in urothelial carcinoma
| Autor: | Mahander Pall, Javid Iqbal, Shrawan Kumar Singh, Satya Vati Rana |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Urology Annals, Vol 4, Iss 2, Pp 98-101 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0974-7796 0974-7834 |
| DOI: | 10.4103/0974-7796.95555 |
| Popis: | Introduction: CA 19-9 is a carbohydrate antigen related to Lewis A blood group antigen. It is well-known marker for pancreatic carcinoma and is being investigated for other malignancies including carcinoma bladder. We evaluated the role of serum CA 19-9 as a tumor marker and correlated its level with tumor stage and grade. Materials and Methods: Seventy-five patients with histologically proven urothelial carcinoma were included in this study as case and 25 healthy volunteers as control. Preoperative 5 ml blood sample was collected. Serum level of CA 19-9 was measured using solid-phase enzyme-linked immunosorbent assay kit. The value of CA19-9 was expressed in U/ml and 37 U/ml was taken as cut-off upper value of normal. Results: The range of CA19-9 in patients of urothelial carcinoma was 2 to 122 U/ml with a mean of 26.33±29.28, while in control, it was 8.48±5.01 U/ml (P |
| Databáze: | Directory of Open Access Journals |
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