A NEW SECO-LIMONOID FROM THE INFLORESCENCES OF Dictyoloma vandellianum

Autor: Laiane Caline Oliveira Pereira, Lucas Silva Abreu, Mayra Bitencourt Silveira, Yuri Mangueira do Nascimento, Thalisson Amorim de Souza, Mireille Le Hyaric, Thaís Mangeon Honorato Lisboa, Marianna Vieira Sobral, Eudes da Silva Velozo, Josean Fechine Tavares, Marcelo Sobral da Silva
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2020
Předmět:
Zdroj: Química Nova, Vol 43, Iss 5, Pp 568-571 (2020)
Druh dokumentu: article
ISSN: 1678-7064
0100-4042
DOI: 10.21577/0100-4042.20170515
Popis: Phytochemical investigation of the inflorescences of Dictyoloma vandellianum A. Juss. (Rutaceae) has led to the isolation of a new A-seco-limonoid, named dictyolomol (1), along with a known quinolone alkaloid, casimiroine (2), previously isolated from the same species. The structures were established by spectroscopic analysis such as one- and two-dimensional NMR, IR, high-resolution mass spectrometry and chemical transformations. The isolated compounds (1 and 2) and O-acetyl derivative (1a) were evaluated for their cytotoxicity against MCF-7 and HeLa cancer cell lines. The results indicated that 1, 1a and 2 showed no significant cytotoxicity.
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