A NEW SECO-LIMONOID FROM THE INFLORESCENCES OF Dictyoloma vandellianum
Autor: | Laiane Caline Oliveira Pereira, Lucas Silva Abreu, Mayra Bitencourt Silveira, Yuri Mangueira do Nascimento, Thalisson Amorim de Souza, Mireille Le Hyaric, Thaís Mangeon Honorato Lisboa, Marianna Vieira Sobral, Eudes da Silva Velozo, Josean Fechine Tavares, Marcelo Sobral da Silva |
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Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Química Nova, Vol 43, Iss 5, Pp 568-571 (2020) |
Druh dokumentu: | article |
ISSN: | 1678-7064 0100-4042 |
DOI: | 10.21577/0100-4042.20170515 |
Popis: | Phytochemical investigation of the inflorescences of Dictyoloma vandellianum A. Juss. (Rutaceae) has led to the isolation of a new A-seco-limonoid, named dictyolomol (1), along with a known quinolone alkaloid, casimiroine (2), previously isolated from the same species. The structures were established by spectroscopic analysis such as one- and two-dimensional NMR, IR, high-resolution mass spectrometry and chemical transformations. The isolated compounds (1 and 2) and O-acetyl derivative (1a) were evaluated for their cytotoxicity against MCF-7 and HeLa cancer cell lines. The results indicated that 1, 1a and 2 showed no significant cytotoxicity. |
Databáze: | Directory of Open Access Journals |
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