The first experience in using rituximab in Mikulicz's disease

Autor: V I Vasilyev, S G Palshina, M V Simonova, O A Logvinenko, S Kh Sedyshev, B V Mitrikov, N A Probatova, N V Kokosadze, T N Safonova, E N Aleksandrova, E L Nasonov
Jazyk: ruština
Rok vydání: 2010
Předmět:
Zdroj: Терапевтический архив, Vol 82, Iss 6, Pp 62-66 (2010)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: The paper describes a case of Mikulicz's disease (MD) in a young woman (aged 19 years) with symmetrical large salivary gland lesion concurrent with the enlarged lacrimal glands. Immunomorphological and molecular studies of parotid gland biopsy specimens revealed the formation of MALT tissue without signs of B-cell clonality of an infiltrate. The diagnosis of lacrimal sac lymphoma was ruled out. MD was diagnosed. The use of rituximab in therapy for MD has first demonstrated a positive result in Russian and worldwide practice.
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