The first experience in using rituximab in Mikulicz's disease
Autor: | V I Vasilyev, S G Palshina, M V Simonova, O A Logvinenko, S Kh Sedyshev, B V Mitrikov, N A Probatova, N V Kokosadze, T N Safonova, E N Aleksandrova, E L Nasonov |
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Jazyk: | ruština |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Терапевтический архив, Vol 82, Iss 6, Pp 62-66 (2010) |
Druh dokumentu: | article |
ISSN: | 0040-3660 2309-5342 |
Popis: | The paper describes a case of Mikulicz's disease (MD) in a young woman (aged 19 years) with symmetrical large salivary gland lesion concurrent with the enlarged lacrimal glands. Immunomorphological and molecular studies of parotid gland biopsy specimens revealed the formation of MALT tissue without signs of B-cell clonality of an infiltrate. The diagnosis of lacrimal sac lymphoma was ruled out. MD was diagnosed. The use of rituximab in therapy for MD has first demonstrated a positive result in Russian and worldwide practice. |
Databáze: | Directory of Open Access Journals |
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