Bullous pemphigoid and comorbidities: a case-control study in Portuguese patients
| Autor: | Vera Barreto Teixeira, Rita Cabral, Maria Manuel Brites, Ricardo Vieira, Américo Figueiredo |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Anais Brasileiros de Dermatologia, Vol 89, Iss 2, Pp 274-278 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0365-0596 1806-4841 |
| DOI: | 10.1590/abd1806-4841.20142516 |
| Popis: | BACKGROUND: aAlthough rare, bullous pemphigoid (BP) is the most common autoimmune blistering disease. Recent studies have shown that patients with bullous pemphigoid are more likely to have neurological and psychiatric diseases, particularly prior to the diagnosis of bullous pemphigoid. OBJECTIVE: The aims were: (i) to evaluate the demographic and clinical features of bullous pemphigoid from a database of patients at a Portuguese university hospital and (ii) to compare the prevalence of comorbid conditions before the diagnosis of bullous pemphigoid with a control group. METHODS: Seventy-seven patients with bullous pemphigoid were enrolled in the study. They were compared with 176 age- and gender-matched controls, which also had the same inpatient to outpatient ratio, but no history of bullous or cutaneous malignant disease. Univariate and multivariate analyses were used to calculate odds ratios for specific comorbid diseases. RESULTS: At least one neurologic diagnosis was present in 55.8% of BP patients compared with 20.5% controls (p |
| Databáze: | Directory of Open Access Journals |
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