Long term outcome of medical and surgical co-management of craniospinal aspergillosis in an immunocompromised patient

Autor: Dipu Sathyapalan, Sabarish Balachandran, Anil Kumar, Bindu Mangalath Rajamma, Ashok Pillai, Vidya P. Menon
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 14, Iss C, Pp 33-37 (2016)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2016.11.008
Popis: 35 yr old steroid dependent lady with Pulmonary TB underwent debridement of epidural abscess & posterior stabilization for paraparesis. With histopathology and cultures showing Aspergillus fumigatus, voricanozole was started. By the fourth week, she developed persistent fever, and altered mental status. Brain MRI and CSF study including multiplex PCR evaluation confirmed cerebral aspergillosis. Voricanozole was changed to intravenous lipid complex Amphotericin B to achieve sustained clinical and radiological response after six months of therapy.
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