| Autor: |
Baptiste Thomas, Michele Fiore, Isabelle Bossu, Pascal Dumy, Olivier Renaudet |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 421-427 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.8.47 |
| Popis: |
Synthetic heteroglycoclusters are being subjected to increasing interest due to their potential to serve as selective ligands for carbohydrate-binding proteins. In this paper, we describe an expedient strategy to prepare cyclopeptides displaying well-defined distributions and combinations of carbohydrates. By using both oxime ligation and copper(I)-catalyzed alkyne–azide cycloaddition, two series of compounds bearing binary combinations of αMan, αFuc or βLac in an overall tetravalent presentation, and either 2:2 or 3:1 relative proportions, have been prepared. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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