| Autor: |
Hugh Sparks, Hiroshi Kondo, Steven Hooper, Ian Munro, Gordon Kennedy, Christopher Dunsby, Paul French, Erik Sahai |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-04820-6 |
| Popis: |
The engagement of DNA-binding drugs to their target is difficult to study, particularly in vivo. Here the authors develop an in vivo fluorescence lifetime imaging confocal laparo/endomicroscope to show intra- and inter-tumor heterogeneity in doxorubicin binding to peritoneal metastases, which depends on the route of administration. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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