Associations Between Albuminuria and Mortality Among US Adults by Demographic and Comorbidity Factors

Autor: Yelena Drexler, Julien Tremblay, Robert A. Mesa, Bailey Parsons, Efren Chavez, Gabriel Contreras, Alessia Fornoni, Leopoldo Raij, Samuel Swift, Tali Elfassy
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.123.030773
Popis: Background Albuminuria is a known marker of mortality risk. Whether the association between albuminuria and mortality differs by demographic and comorbidity factors remains unclear. Therefore, we sought to determine whether albuminuria is differentially associated with mortality. Methods and Results This study included 49 640 participants from the National Health and Nutrition Examination Survey (1999–2018). All‐cause mortality through 2019 was linked from the National Death Index. Multivariable‐adjusted Poisson regression models were used to determine whether levels of urine albumin‐to‐creatinine ratio (ACR) were associated with mortality. Models were adjusted for demographic, socioeconomic, behavioral, and clinical factors. Mean age in the population was 46 years, with 51.3% female, and 30.3% with an ACR ≥10 mg/g. Over a median follow‐up of 9.5 years, 6813 deaths occurred. Compared with ACR
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