Melanoma of the sinonasal mucosa: A report on the two cases and a review of the literature

Autor: Aleksić Aleksandra, Gajanin Radoslav, Đurđević Dejan, Novaković Zorica, Vranješ Dalibor, Spremo Slobodan, Travar Dmitar, Guzina-Golac Nataša, Tomić-Spirić Vesna
Jazyk: English<br />Serbian
Rok vydání: 2015
Předmět:
Zdroj: Vojnosanitetski Pregled, Vol 72, Iss 10, Pp 937-941 (2015)
Druh dokumentu: article
ISSN: 0042-8450
2406-0720
DOI: 10.2298/VSP140414075A
Popis: Introduction. Primary mucosal melanoma of the sinonasal tract is a rare neoplasm, accounting for less than 1% of all melanomas. It has an aggressive and unpredictable biologic behavior characterized by frequent incidence of local recurrence, local and distant metastasis of the disease. Case report. This report summarizes the results of the previous research concerning sinonasal mucosal melanoma, and by the example of the two patients suffering from mucosal melanoma, we described clinical and histopathological features of this rare neoplasm and our experience in its diagnosis and treatment. Conclusion. Only histopathological analysis complemented by immunohistochemical analysis contributes to early and accurate diagnosis of the disease.
Databáze: Directory of Open Access Journals