Contrast visual acuity in patients with retinitis pigmentosa assessed by a contrast sensitivity tester
| Autor: | Maho Oishi, Hajime Nakamura, Masanori Hangai, Akio Oishi, Atsushi Otani, Nagahisa Yoshimura |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Accommodation
disaccommodation mydriasis phenylephrine hydrochloride pupil velocity Growth human adult lens diameter lens dry weight lens thickness lens wet weight Silicone oil removal encirclage 360 retinopexy oil emulsification silicone oil tamponade Age-related macular degeneration chorodial neovascularization ocular trauma polypoidal choroidal vasculopathy retinal macroaneurysm submacular hemorrhage subretinal hemorrhage tissue plasminogen activator vitrectomy Insulin-like growth factor-1 insulin-like growth factor binding protein-3 retinopathy of prematurity Brilliant Blue G dextrose normal saline 10% internal limiting membrane macular hole Angle closure anterior chamber angle blotchy pigments glaucomatous optic neuropathy peripheral anterior synechiae Cardiff acuity cards lea grating visual acuity in pre-verbal children Contrast sensitivity contrast visual acuity retinitis pigmentosa Ophthalmology RE1-994 |
| Zdroj: | Indian Journal of Ophthalmology, Vol 60, Iss 6, Pp 545-549 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| DOI: | 10.4103/0301-4738.103793 |
| Popis: | Purpose: To assess contrast visual acuity (CVA) in patients with retinitis pigmentosa (RP) and compare the result with standard visual acuity (VA), retinal thickness, status of inner segment/outer segment junction, and central visual field. Materials and Methods: Thirty-nine eyes of 39 patients with RP and 39 eyes of 39 healthy individuals were studied. To see the difference in CVA between RP patients and normal controls, only subjects with standard VA of 1.0 (20/20) or better were included. This was a cross-sectional study. CVA in various light conditions was measured with CAT-2000 and was compared between patients and controls. CVA of patients was further analyzed for association with other parameters including foveal retinal thickness, outer nuclear layer thickness, the status of inner segment/outer segment junction measured with optical coherence tomography (OCT), and visual field mean deviation (MD) measured with Humphrey field analyzer 10-2 program. Results: CVA impairment was evident in RP patients compared to controls (P < 0.01, in all measurement conditions). Multivariate analysis showed association of logarithm of the minimum angle of resolution (logMAR) with CVAs in several conditions. None of the OCT measurements was associated with CVA. When patients were divided into three groups based on MD, the most advanced group (MD worse than or equal to –20 dB) showed impairment of mesopic CVA (P < 0.05, under mesopic condition of 100% without glare, with glare, and 25% without glare). Conclusion: CVA impairment was confirmed in RP patients, especially in advanced cases. CVA measured with CAT-2000 may be a useful tool for assessing foveal function in RP patients. |
| Databáze: | Directory of Open Access Journals |
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