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Autor: LIN Yao, HUANG Jing, XUE Xiaojuan, ZHANG Huan, FENG Bin
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: 口腔疾病防治, Vol 30, Iss 5, Pp 350-354 (2022)
Druh dokumentu: article
ISSN: 2096-1456
DOI: 10.12016/j.issn.2096-1456.2022.05.007
Popis: Objective To analyze the adverse drug reaction(ADR) reports of hydroxychloroquine for clinical medication safety. Methods The ADR reports of hydroxychloroquine between May 2019 and May 2021 were analyzed. Age, reasons for drug use, time of ADR, combined drug use, and ADR outcomes were statistically analyzed. Results No severe ADR was reported. Patients over 60 years old accounted for 53.85% of the total cases, and the time of ADR appearance was significantly earlier among those under 60 years old. A total of 61.54% of ADRs were involved in multiple organs, and optic neurotoxicity was reported in 46.15% of cases. Conclusion In the treatment of oral lichen planus with hydroxychloroquine, adverse drug reactions should be monitored, and increased attention should be given to patients over 60 years old to ensure the safety of this medication.
Databáze: Directory of Open Access Journals