| Autor: |
Dajana Lendak, Pedro Puerta-Alcalde, Estela Moreno-García, Mariana Chumbita, Nicole García-Pouton, Celia Cardozo, Laura Morata, Maria Suárez-Lledó, Marta Hernández-Meneses, Lucio Ghiglione, Francesc Marco, Jose Antonio Martinez, Josep Mensa, Ivana Urošević, Alex Soriano, Carolina Garcia-Vidal |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 16, Iss 4, p e0251010 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0251010 |
| Popis: |
BackgroundWe aimed to describe the epidemiology of catheter-related bloodstream infections (CRBSIs) in onco-hematological neutropenic patients during a 25-year study period, to evaluate the risk factors for Gram-negative bacilli (GNB) CRBSI, as well as rates of inappropriate empirical antibiotic treatments (IEAT) and mortality.Materials/methodsAll consecutive episodes of CRBSIs were prospectively collected (1994-2018). Changing epidemiology was evaluated comparing five-year time spans. A multivariate regression model was built to evaluate risk factors for GNB CRBSIs.Results482 monomicrobial CRBSIs were documented. The proportion of CRBSIs among all BSIs decreased over time from 41.2% to 15.8% (pConclusionA significant shift towards GNB-CRBSIs was observed. Secondarily, and coinciding with an increasing number of GNB-MDR infections, mortality increased over time. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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