Areas of Uncertainty in SARS-CoV-2 Vaccination for Cancer Patients
Autor: | Anastasios Dimou |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Vaccines, Vol 10, Iss 12, p 2117 (2022) |
Druh dokumentu: | article |
ISSN: | 10122117 2076-393X |
DOI: | 10.3390/vaccines10122117 |
Popis: | Early in the COVID-19 pandemic, it was recognized that infection with SARS-CoV-2 is associated with increased morbidity and mortality in patients with cancer; therefore, preventive vaccination in cancer survivors is expected to be particularly impactful. Heterogeneity in how a neoplastic disease diagnosis and treatment interferes with humoral and cellular immunity, however, poses a number of challenges in vaccination strategies. Herein, the available literature on the effectiveness of COVID-19 vaccines among patients with cancer is critically appraised under the lens of anti-neoplastic treatment optimization. The objective of this review is to highlight areas of uncertainty, where more research could inform future SARS-CoV-2 immunization programs and maximize benefits in the high-risk cancer survivor population, and also minimize cancer treatment deviations from standard practices. |
Databáze: | Directory of Open Access Journals |
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