The relation between lead exposure and inflammation / endothelial dysfunction

Autor: Lutfiye Tutkun, Meside Gunduzoz, Ozgur Oztan, Vugar Ali Turksoy, Mehmet Erdem Alaguney, Servet Birgin Iritas
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Medicine Science, Vol 9, Iss 2, Pp 468-72 (2020)
Druh dokumentu: article
ISSN: 2147-0634
DOI: 10.5455/medscience.2020.08.9249
Popis: Pb exposure is a well-known risk factor for inflammation including vessels. In our study, we aimed to investigate the relationship between Pb levels of exposed workers and the severity of inflammation/endothelial dysfunction. We analyzed the correlation between blood lead level and the markers of endothelial damage. There was a significant correlation between blood lead levels and vascular cell adhesion molecule-1 (VCAM-1). Elevated levels of blood lead also show correlation with soluble CD40 ligand (sCD40L). The strongest correlation was with sE-selectin. Association between lead exposure and markers of cardiovascular injury may help to predict cardiovascular effects of lead earlier and to protect workers who are exposed to lead. [Med-Science 2020; 9(2.000): 468-72]
Databáze: Directory of Open Access Journals