Synthesis and Characterization of Two Danazol Derivatives
| Autor: | Lauro Figueroa-Valverde, francisco Díaz-Cedillo, Maria López-Ramos, Elodia Garcia-Cervera |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | E-Journal of Chemistry, Vol 7, Iss S1, Pp S191-S196 (2010) |
| Druh dokumentu: | article |
| ISSN: | 0973-4945 2090-9810 |
| DOI: | 10.1155/2010/853298 |
| Popis: | Two danazol derivatives were synthesized and characterized by spectral analyses. In order to characterize the structural and chemical requirements of danazol derivatives, several parameters such as logP, π, Rm and Vm were evaluated. The results showed an increase in the values of logP for the compound 6 in comparison with 3. The compound 3 showed an increase in the values of π, R Vm and V Vm with respect to 6. These data indicate a high degree of lipophilicity and a low steric impediment for compound 6 in comparison with 3. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|