Evaluation of Cucurbita pepo L. seeds used in folk medicine for their anti-inflammatory and wound healing activity

Autor: Cigdem Kahraman, Golshan Zare, Serap Arabaci, Esra Kupeli Akkol, Iffet Irem Tatli Cankaya
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Medicine Science, Vol 9, Iss 2, Pp 381-4 (2020)
Druh dokumentu: article
ISSN: 2147-0634
DOI: 10.5455/medscience.2019.08.9212
Popis: Since Cucurbita pepo L. seeds have been reported to have beneficial effects in folk medicine for many years, in this study, in vivo wound healing activities of diethyl ether, chloroform and ethyl acetate extracts prepared from C. pepo seeds were evaluated by linear incision wound model, and hydroxyproline content. Furthermore, the extracts were screened for anti-inflammatory activity based on the inhibition of acetic acid-induced capillary permeability. The ethyl acetate extract had the highest inhibitory effect on acetic acid-induced capillary permeability, but the rest of the extracts didnt display significant anti-inflammatory activity. On the other hand, according to the activity using linear incision wound model as well as hydroxyproline content of the treated tissue, all three extracts did not indicate wound healing activity. [Med-Science 2020; 9(2.000): 381-4]
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