Association of X Chromosome Aberrations with Male Infertility

Autor:	Xharra S., Behluli E., Moder A., Nefic H., Hadziselimovic R., Temaj G.
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	klinefelter syndrome azoospermia chromosome aberration androgen receptors y chromosome x chromosome Medicine
Zdroj:	Acta Medica Bulgarica, Vol 48, Iss 4, Pp 69-72 (2021)
Druh dokumentu:	article
ISSN:	2719-5384 2021-0051
DOI:	10.2478/amb-2021-0051
Popis:	Male infertility is caused by spermatogenetic failure, clinically noted as oligoor azoospermia. Approximately 20% of infertile patients carry a genetic defect. The most frequent genetic defect leading to azoospermia (or severe oligozoospermia) is Klinefelter syndrome (47, XXY), which is numerical chromosomal abnormality and Y- structural chromosome aberration. The human X chromosome is the most stable of all human chromosomes. The X chromosome is loaded with regions of acquired, rapidly evolving genes. The X chromosome may actually play an essential role in male infertility and sperm production. Here we will describe X chromosome aberrations, which are associated with male infertility.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/164e01ed5c1c4489bcea8068ba2b2643 Zobrazit plný text záznamu View record in DOAJ