Diethylstilbestrol 1 mg in the Treatment of Acute Urinary Retention due to Prostatic Obstruction in the Elderly: A Preliminary Study
| Autor: | Leonardo Oliveira Reis, Gustavo Borges De Mendonça, Bruno D. Carneiro, Edson Schneider, Eduardo Varella Gewehr, André Meirelles, Fernandes Denardi, Antonio Gugliotta |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Advances in Urology, Vol 2014 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1687-6369 1687-6377 |
| DOI: | 10.1155/2014/984382 |
| Popis: | Patients who failed a catheter-free trial after acute urinary retention and one week of full dose alpha-blocker and 5-alpha-reductase inhibitor were offered Diethylstilbestrol 1 mg plus Aspirin 100 mg over 4 weeks. Prostate volume, age, serum creatinine, and initial retention drained urine volume were recorded. After excluding cardiovascular morbidity (n=7), upper urinary tract dilation (n=3), compromised renal function (n=2), urinary tract infection (n=2), neurological diagnosis (n=2), or preferred immediate channel transurethral resection of prostate (n=5), 48 of 69 consecutive patients ≥70 years were included. Mean age was 76.6 years (70–84), mean prostate volume 90 cm3 (42–128), and mean follow-up 204 days; 58% (28/48) were passing urine and 42% (20/48) were catheter dependent after 4 weeks Diethylstilbestrol trial. Mean age and drained urine volume of catheter dependent patients were 82.4 years and 850 mL compared with 74.6 years and 530 mL in catheter-free men, respectively. Age and drained urine volume were independent predictors of catheter-free trial (both P |
| Databáze: | Directory of Open Access Journals |
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