Ocular Manifestations of West Nile Virus

Autor: Antoine Rousseau, Oscar Haigh, Imen Ksiaa, Moncef Khairallah, Marc Labetoulle
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Vaccines, Vol 8, Iss 4, p 641 (2020)
Druh dokumentu: article
ISSN: 2076-393X
DOI: 10.3390/vaccines8040641
Popis: Ocular manifestations are a feature of West Nile virus infection. They mostly occur in association with severe neuroinvasive disease. Linear chorioretinitis is suggestive of the diagnosis and may raise diagnostic suspicion when associated with evocative systemic signs, and in an epidemic context. Various other less specific inflammatory ocular manifestations have been reported, including anterior uveitis, occlusive retinal vasculitis, optic neuritis, and diplopia. The pathophysiology of ocular disease remains unclear, but it reflects the neuroinvasiveness of the disease. Although ocular involvement most often resolves without visual sequelae, some patients may have permanent loss of vision, adding to the need for the development of a specific treatment and/or vaccines.
Databáze: Directory of Open Access Journals