| Autor: |
Mirza Asif Baig |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Indian Journal of Pathology and Microbiology, Vol 63, Iss 2, Pp 247-250 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0377-4929 |
| DOI: |
10.4103/IJPM.IJPM_899_19 |
| Popis: |
Background: Thrombophilia is a hypercoagulable state characterized by increased venous thrombosis. The most common cause of heritable thrombophilia is Factor V Leiden (FVR506Q) homozygous state, with a relative risk of 10–80 times as compared to normal individuals and Lupus anticoagulant is the most common cause of acquired thrombophilia. The main objective of this study is to compare the sensitivity of activated partial thromboplastin time (APTT) vs dilute Russell viper venom test (DRVVT) based APCR assays with predilution in Factor V-deficient plasma for diagnosis of Factor V Leiden mutation. Materials And Methods: The coagulometer used for APCR test was Sysmex CS-5100. APTT reagent used is Pathrombin SL supplied by Siemens. All data were expressed as mean ± SD. Statistical analysis was done using unpaired students t-test and a P value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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