Comparison of Efficacy of Topical Cprofloxacin Ear Drops 0.6% Versus Oral Cprofloxacin 500 mg Twice Daily in Achieving Dry Ear in Chronic Suppurative Otitis Medi

Autor: Muhammad Imran Malik, Aiman Fatima Naqvi, Zaimal Shahan, Amir Akbar, Amna Enam, Mohsin Raza
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 74, Iss 4 (2024)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
DOI: 10.51253/pafmj.v74i4.10016
Popis: Objective: To compare the efficacy of Cprofloxacin 0.6% ear drops versus oral Cprofloxacin in achieving the dry ears in chronic suppurative otitis media patients presenting at a tertiary care hospital, Islamabad Pakistan. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Otorhinolaryngology and Head and Neck Surgery, Pakistan Institute of Medical Sciences, Islamabad Pakistan, from Jun 2022 to Dec 2022. Methodology: The study recruited 130 patients with unilateral or bilateral chronic ear discharge, of either gender, aged 12-60 years, and divided them into two groups of 65 each. Group-A received topical Cprofloxacin 0.6% in a dose of four drops three times per day, while Group-B, 65 patients received oral Cprofloxacin 500 mg twice daily. Otoscopy was used to monitor patients for two weeks following dry ear treatment. Results: The mean age of participants was 29.70±9.03 years and most patients were males (60%). Post-treatment results of Group-A revealed that there were 11(16.9%) subjects with ear discharge. The rest 54(83.1%) had no ear discharge. In Group-B, there were 46(70.8%) subjects with ear discharge. The rest 19(29.2%) had no ear discharge. A statistically significant (p=0.001) difference in efficacy was observed between both groups. Conclusion: Topical Cprofloxacin 0.6% given 6 drops twice daily for two weeks is a better choice in medical management of CSOM than oral Cprofloxacin 500mg twice daily in terms of resolution of ear discharge.
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