Analysis of spontaneous reporting of suspected adverse drug reactions for non-analgesic over-the-counter drugs from 2008 to 2017

Autor: Josipa Bukic, Doris Rusic, Petar Mas, Deni Karabatic, Josko Bozic, Ana Seselja Perisin, Dario Leskur, Darko Krnic, Sinisa Tomic, Darko Modun
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 2050-6511
DOI: 10.1186/s40360-019-0338-2
Popis: Abstract Background Adverse drug reaction (ADR) reporting practices by health care professionals remain poor. Over-the-counter (OTC) drugs are perceived as safe; however, they can also cause ADRs. The objective of this study was to analyze ADR reporting for OTC drugs in a 10-year period, in order to evaluate frequency of ADRs, population that ADRs most affect and reporters of ADRs of OTC drugs in Croatia. Methods Spontaneously reported ADRs of non-analgesic OTC drugs, collected from January 2008 to December 2017 were analyzed. Data was obtained from Agency for Medicinal Products and Medical Devices of Croatia (HALMED). Results There were 547 ADRs of OTC drugs reported in total and an increase in number of reports through the years was observed. Pharmacists reported 45.4% of all ADRs, and were most frequent reporters (p
Databáze: Directory of Open Access Journals