Use of biological Glue (Bioglue®) in laparoscopic partial nephrectomy: a study in pigs

Autor: Luis Felipe Brandão, Fabio Cesar Miranda Torricelli, Glauco Melo, Luiz Fernando Takano, Anuar Ibrahim Mitre, Marco Antonio Arap
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: International Brazilian Journal of Urology, Vol 41, Iss 2, Pp 252-257 (2015)
Druh dokumentu: article
ISSN: 1677-6119
1677-5538
DOI: 10.1590/S1677-5538.IBJU.2015.02.10
Popis: Introduction Partial nephrectomy is the standard of care for localized renal tumors. However, bleeding and warm ischemia time are still controversial when laparoscopic surgeries are carried out. Herein, we aim to compare the outcomes from laparoscopic partial nephrectomy with and without the use of biological glue with purified bovine albumin and glutaraldehyde (BioGlue®). Materials and Methods Twenty-four kidneys of 12 pigs were used in this study. A pre-determined lower pole segment was resected (3 cm x 1 cm) and one of two different hemostatic techniques was performed. In one kidney, hemostatic “U suture” (poliglecaprone 3.0) was performed and in the contra-lateral kidney, only the biological glue was applied. Data recorded was comprised of warm ischemia time (seconds) and estimated blood loss (mL) for each procedure. In cases of bleeding after glue administration, a complementary suture was done. Results Mean warm ischemia time was 492.9±113.1 (351-665) seconds and 746±185.3 (409-1125) seconds for biological glue and suture groups, respectively. There was a positive significant difference in terms of warm ischemia favoring the biological glue group over the suture group (p
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