Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides

Autor: Ana Maranha, Mafalda Costa, Jorge Ripoll-Rozada, José A. Manso, Vanessa Miranda, Vera M. Mendes, Bruno Manadas, Sandra Macedo-Ribeiro, M. Rita Ventura, Pedro José Barbosa Pereira, Nuno Empadinhas
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-023-04448-3
Popis: The mechanism of methylmannose polysaccharide (MMP) biogenesis in nontuberculous mycobacteria (NTM) is characterized, which involves an MMP-specific hydrolase (MmpH) and a rare mannosyltransferase (ManT). MmpH and ManT structures are presented.
Databáze: Directory of Open Access Journals
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