Dry eye disease immune responses and topical therapy

Autor: Charles W. McMonnies
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Eye and Vision, Vol 6, Iss 1, Pp 1-4 (2019)
Druh dokumentu: article
ISSN: 2326-0254
DOI: 10.1186/s40662-019-0137-2
Popis: Abstract There is accumulating evidence that inflammation is one of the key components of dry eye because chronic ocular surface inflammation can be both a result as well as an initiator of dry eye. The need for continuing anti-inflammatory therapy may be determined in part by the extent that non-modifiable factors such as gender and age-related aqueous or lipid or mucus production deficiencies contribute to its chronicity. This perspective examines how the need for increased dosage of a topical anti-inflammatory drug may be determined by the degree of difficulty that a topically administered drug has in accessing different sites of tear deficiency and associated inflammation.
Databáze: Directory of Open Access Journals