THE EFFECT OF FICUS CARICA ON LEAD ACETATE INDUCED CHANGES IN THE HEIGHT OF GERMINAL EPITHELIUM OF SEMINIFEROUS TUBULES OF ADULT RAT TESTES
| Autor: | Ayesha Asad, Afnan Gul, Maria Yousaf, Khadija Qamar |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Pakistan Armed Forces Medical Journal, Vol 69, Iss 2, Pp 378-382 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0030-9648 2411-8842 |
| Popis: | Objective: To evaluate the effect of Ficus carica on lead acetate induced changes in the height of germinal epithelium of seminiferous tubules in testes of adult rats. Study Design: Randomized controlled trial. Place and Duration of Study: The study was conducted for a period of 8 weeks at Departments of Anatomy and Pathology, Army Medical College, Rawalpindi in collaboration with National Institute of Health (NIH), Islamabad Pakistan. Material and Methods: Thirty healthy adult male Sprague-dawley rats were selected by simple random sampling and divided into three groups. Each group consisted of 10 animals. Group A served as control. Group B was given lead acetate 30 mg/kg body weight/day. Group C received Ficus carica 80 mg/kg bodyweight/day in addition to lead acetate 30 mg/kg bodyweight/ day. The dose was administered once a day for a period of 8 weeks. Twenty-four hours after administration of last dose, the animals were sacrificed and testes were removed. Testicular tissue was processed and stained with haematoxylin and eosin. Height of germinal epithelium of the seminiferous tubules was measured. The data was analyzed using SPSS version 22. Results were considered significant at p-value |
| Databáze: | Directory of Open Access Journals |
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