Applying the digital data and the bioinformatics tools in SARS-CoV-2 research

Autor: Meng Tan, Jiaxin Xia, Haitao Luo, Geng Meng, Zhenglin Zhu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4697-4705 (2023)
Druh dokumentu: article
ISSN: 2001-0370
DOI: 10.1016/j.csbj.2023.09.044
Popis: Bioinformatics has been playing a crucial role in the scientific progress to fight against the pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The advances in novel algorithms, mega data technology, artificial intelligence and deep learning assisted the development of novel bioinformatics tools to analyze daily increasing SARS-CoV-2 data in the past years. These tools were applied in genomic analyses, evolutionary tracking, epidemiological analyses, protein structure interpretation, studies in virus-host interaction and clinical performance. To promote the in-silico analysis in the future, we conducted a review which summarized the databases, web services and software applied in SARS-CoV-2 research. Those digital resources applied in SARS-CoV-2 research may also potentially contribute to the research in other coronavirus and non-coronavirus viruses.
Databáze: Directory of Open Access Journals