Primary Hepatic Choriocarcinoma with Pregnancy: A Diagnostic and Therapeutic Challenge
| Autor: | Amith Kumar Pakkala, Phani Kumar Nekarakanti, Bheerappa Nagari, Ashish Kumar Bansal, Gourang Shroff, Megha S Uppin |
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| Jazyk: | English<br />Korean |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | The Korean Journal of Gastroenterology, Vol 81, Iss 2, Pp 91-94 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1598-9992 2233-6869 |
| DOI: | 10.4166/kjg.2022.116 |
| Popis: | Choriocarcinoma occurs mainly in the gonads, but an extragonadal origin has been reported, albeit infrequently. Primary hepatic choriocarcinoma (PHC) is a rare malignancy, with only 11 cases reported. Most cases reported were in males, with none reported in pregnant females. A 23-year-old primigravida presented with a large liver lesion involving the right lobe of the liver at 28 weeks of pregnancy. Preoperative imaging was suggestive of hepatocellular carcinoma. She underwent a non-anatomical resection of the liver lesion. Surprisingly, her postoperative histopathology revealed a diagnosis of PHC. Her blood workup showed elevated beta human chorionic gonadotrophin. She underwent a termination of her pregnancy at 32 weeks. Before initiating adjuvant chemotherapy four weeks after surgery, a whole-body PET scan revealed multiple bi-lobar liver and pelvic deposits. After a multidisciplinary team discussion, she was started on adjuvant chemotherapy. She is currently under regular follow-up, seven months post-surgery. PHC, one of the vascular lesions of the liver, poses a diagnostic and therapeutic challenge, warranting a multidisciplinary approach. |
| Databáze: | Directory of Open Access Journals |
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