Serum osteoprotegerin as an early marker of chronic kidney disease in hypertensive patients

Autor: Khaled A Elhefnawy, Ezzat M Mohamed, Athar M Abou Yousef, Abeer A Fikry, Hala M Allam
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: The Egyptian Journal of Internal Medicine, Vol 31, Iss 4, Pp 922-926 (2019)
Druh dokumentu: article
ISSN: 1110-7782
2090-9098
DOI: 10.4103/ejim.ejim_169_19
Popis: Background Serum osteoprotegerin (OPG) is a marker of cardiovascular disease. The deterioration of renal function in diabetic patients could be predicted by OPG concentrations, and it was suggested that OPG could be used as a risk marker for chronic kidney disease (CKD) in patients with hypertension. Objective The aim was to investigate the role of serum OPG as an early marker of CKD in hypertensive patients. Patients and methods A total of 144 hypertensive patients were included and classified into two main groups: group I, which included 72 hypertensive patients without CKD [estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2], and group II, which included 72 hypertensive patients with CKD (eGFR
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