Serum osteoprotegerin as an early marker of chronic kidney disease in hypertensive patients
Autor: | Khaled A Elhefnawy, Ezzat M Mohamed, Athar M Abou Yousef, Abeer A Fikry, Hala M Allam |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | The Egyptian Journal of Internal Medicine, Vol 31, Iss 4, Pp 922-926 (2019) |
Druh dokumentu: | article |
ISSN: | 1110-7782 2090-9098 |
DOI: | 10.4103/ejim.ejim_169_19 |
Popis: | Background Serum osteoprotegerin (OPG) is a marker of cardiovascular disease. The deterioration of renal function in diabetic patients could be predicted by OPG concentrations, and it was suggested that OPG could be used as a risk marker for chronic kidney disease (CKD) in patients with hypertension. Objective The aim was to investigate the role of serum OPG as an early marker of CKD in hypertensive patients. Patients and methods A total of 144 hypertensive patients were included and classified into two main groups: group I, which included 72 hypertensive patients without CKD [estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2], and group II, which included 72 hypertensive patients with CKD (eGFR |
Databáze: | Directory of Open Access Journals |
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