Group B streptococcus neonatal umbilical colonization managed by dry cord care in nurseries: A retrospective cohort study

Autor: Keigo Takahashi, Yuka Sato, Kazushige Ikeda
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Pediatrics and Neonatology, Vol 62, Iss 5, Pp 506-511 (2021)
Druh dokumentu: article
ISSN: 1875-9572
DOI: 10.1016/j.pedneo.2021.05.003
Popis: Background: Screening-based intrapartum antibiotic prophylaxis (IAP) has reduced the prevalence of early-onset group B Streptococcus (GBS) infection in newborns. Nevertheless, early-onset disease still occurs despite IAP, and IAP is not effective in preventing late-onset disease. This study aimed to determine the prevalence and risk factors of GBS neonatal umbilical colonization managed by dry cord care in Japan. Methods: Of 735 healthy newborns in the well-baby nursery at Saitama City Hospital, 353 from whom umbilical bacterial swabs were obtained before discharge were included in the analysis. Maternal and neonatal clinical characteristics were retrospectively reviewed. Results: GBS was detected in 4.2% (15/353) of umbilical swabs; 13/15 (86.8%) were born to GBS-negative mothers. The median (IQR) age at umbilical swab collection was 4.0 (4.0–5.0) days. Comparison of clinical characteristics between GBS-positive and negative neonates revealed a significant difference in the proportion of vaginal deliveries (15/15 [100%] in GBS-positive neonates vs. 115/338 [34.0%] in GBS-negative neonates, p
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