Beyond cholesterol: Exploring serum ferritin’s and high-sensitivity C-reactive protein role in cardiovascular risk
Autor: | Veena Murthy Goda, Pramodini Garikipati, Jyothi Nunna |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Asian Journal of Medical Sciences, Vol 15, Iss 4, Pp 84-90 (2024) |
Druh dokumentu: | article |
ISSN: | 2467-9100 2091-0576 |
DOI: | 10.3126/ajms.v15i4.61129 |
Popis: | Background: Iron, a pivotal element in the oxidation of low-density lipoprotein (LDL) cholesterol, exerts influence on inflammatory responses and exhibits a positive association with coronary heart disease. Elevated levels of the inflammatory marker, C-reactive protein (CRP), serve as a predictive risk factor for subsequent cardiac events. Aims and Objectives: This study explores the interplay between cardiovascular disease risk factors and serum ferritin concerning CRP. Materials and Methods: A cohort of 750 subjects (375 males and 375 females) was subjected to analysis. Elevated levels were defined as CRP >3.0 mg/L, serum ferritin >200 ng/mL, total cholesterol >200 mg/dL, and LDL-cholesterol >160 mg/dL. HDL cholesterol levels below 40 mg/dL were categorized as low. Results: Within the low LDL-cholesterol group, no discernible correlation was observed between serum ferritin and high-sensitivity CRP (hsCRP) (odds ratio [OR] of 54.95, 95% confidence interval [CI] = 0.81–3.48, P |
Databáze: | Directory of Open Access Journals |
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