| Autor: |
Qi-Hong Sun, Yu Zheng, Xiao-Lin Zhang, Yi-Ming Mu |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Chinese Medical Journal, Vol 128, Iss 18, Pp 2439-2443 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
0366-6999 |
| DOI: |
10.4103/0366-6999.164926 |
| Popis: |
Background: Delayed puberty can result either from constitutional delay of growth and puberty (CDP) or idiopathic hypogonadotropic hypogonadism (IHH). Gonadotropin-releasing hormone (GnRH) stimulation test has been generally accepted as a current method for diagnosing delayed puberty. The objective of this research was to assess the cut-off values and the efficacy of GnRH stimulation test in the diagnosis of delayed puberty in both males and females. Methods: A study of 91 IHH, 27 CDP patients, 6 prepubertal children, and 20 pubertal adults was undertaken. Blood samples were obtained at 0, 30, 60, and 120 min after GnRH administration and the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were measured. For each parameter, the sensitivities and specificities were estimated, and the receiver operating characteristic (ROC) curves were constructed. Results: The ROC curves indicated that a serum basal LH |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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