Early-onset-early-resolving atopic dermatitis does not increase the risk of development of allergic diseases at 3 Years old

Autor: Li-Chieh Wang, Bor-Luen Chiang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of the Formosan Medical Association, Vol 119, Iss 12, Pp 1854-1861 (2020)
Druh dokumentu: article
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2020.02.014
Popis: Background: Epidemiological findings showed the increased risk of allergic rhinitis (AR) and asthma in the children with preceding atopic dermatitis (AD). In this study, we aimed to observe the development of allergic diseases in infantile AD patients. Methods: We followed up the prospective observational cohort enrolling two-to four-month-old exclusively breastfed infants. The presence of physician-diagnosed asthma, AR and AD at age 3 was recorded with the laboratory tests for atopic sensitization. Results: Fifty infantile AD patients and 48 healthy controls were enrolled. The sex, age and parental atopy history were not significantly different between the two groups. At age 3, 21 (42%) patients had persistent AD in the infantile AD group while only 2 (4.2%) patients had newly diagnosed AD in the control group (p
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