Low-Intensity Transcranial Ultrasound Stimulation: Mechanisms of Action and Rationale for Future Applications in Movement Disorders

Autor:	Andrea Guerra, Matteo Bologna
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	transcranial ultrasound stimulation TUS movement disorders Parkinson’s disease essential tremor dystonia Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Brain Sciences, Vol 12, Iss 5, p 611 (2022)
Druh dokumentu:	article
ISSN:	2076-3425
DOI:	10.3390/brainsci12050611
Popis:	Low-intensity transcranial ultrasound stimulation (TUS) is a novel non-invasive brain stimulation technique that uses acoustic energy to induce changes in neuronal activity. However, although low-intensity TUS is a promising neuromodulation tool, it has been poorly studied as compared to other methods, i.e., transcranial magnetic and electrical stimulation. In this article, we first focus on experimental studies in animals and humans aimed at explaining its mechanisms of action. We then highlight possible applications of TUS in movement disorders, particularly in patients with parkinsonism, dystonia, and tremor. Finally, we highlight the knowledge gaps and possible limitations that currently limit potential TUS applications in movement disorders. Clarifying the potential role of TUS in movement disorders may further promote studies with therapeutic perspectives in this field.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a15ca8a06abc4ebea995903356792909 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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