Preliminary study on the relationship between environmental selenium content and myopia among junior school students in Enshi, Hubei Province

Autor: ZHANG Liang, XIANG Yanfang, JIANG Zulin, WEN Fengping
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Zhongguo shipin weisheng zazhi, Vol 35, Iss 9, Pp 1311-1316 (2023)
Druh dokumentu: article
ISSN: 1004-8456
DOI: 10.13590/j.cjfh.2023.09.009
Popis: ObjectiveTo explore the relationship between environmental selenium content and myopia among junior high school students.MethodsA total of 600 junior high school students from selenium-rich, selenium-sufficient, and selenium-deficient areas from Enshi(200 from each area) were randomly selected. The prevalence of myopia, serum selenium, and hair selenium, as well as the glutathioneperoxidase (GSH-Px) and selenoprotein P (SEPP-1) and the selenium distributions of staple crops and drinking water, were determined. The z-test was used to compare continuous data between two groups, a one-way analysis of variance was used to compare continuous data between multiple groups, a chi-square test was used to compare the rates, and the Pearson correlation test was performed to investigate the correlation between selenium and myopia.ResultsAll of the junior school students were divided into myopic (n=244, 40.67%) and non-myopic (n=356, 59.33%) groups. The levels of serum selenium, hair selenium, GSH-Px, and SEPP-1 in the selenium-deficient areas were significantly lower than those in the selenium-adequate areas and the selenium-rich areas [(71.25 ± 10.31)μg/L vs.(86.74 ± 11.25)μg/L vs.(102.31 ± 10.26)μg/L,(0.56 ± 0.20)μg/g vs.(0.72 ± 0.11 )μg/g vs.(0.81 ± 0.12)μg/g,(85.26 ± 15.16)μ/L vs.(95.34 ± 13.20)μ/L vs.(114.65 ± 12.12)μ/L,(7.41 ± 1.65)mg/L vs.(10.25 ± 2.47)mg/L vs.(12.36 ± 3.25)mg/L] (F=9.65, 12.24, 10.32, 9.41, P
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